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Research Study

Biomarkers and intervention study for aging with and without a history of concussion

Does having a history of concussion affect healthy aging?

Closed Recruitment

Health Areas

Alzheimer's Disease, Cognitive impairment, Dementia , Traumatic Brain Injury , Other Diagnosis and Therapy

Study Purpose

Concussions, and other types of mild traumatic brain injuries, are risk factors for dementia. This study aims to explore if biological markers of aging and dementia can distinguish adults with and without histories of concussion. Additionally, this study includes a 12-week cognitive intervention to promote brain health. The intervention is called "NeuroTracker" and is a simple video game that can be done from home!

Details

There are three components in this study. First, a baseline assessment consisting of Magnetic Resonance Imaging (MRI) to look at brain structure, blood and saliva collection to examine markers of inflammation and brain integrity, and cognitive assessments to see how the brain processes information. Second, a 12-week intervention (cognitive training or waitlist control). Third, follow-up assessments (1-week and 6-months) consisting of MRI, blood and saliva collection, and cognitive assessments.

location

Vancouver Island / Coast

Lower Mainland

recruitment end date

2026-04-23

eligibility

Age: 50 Years - 90 Years Old

Accepting Healthy Volunteers: Yes

Research Team Information

Principal investigator

Brian Christie

health authority affiliation

Vancouver Island Health

academic affiliation

University of Victoria

collaborating organizations

University of Montreal

Victoria Brain Injury Society

collaborators

gawryluk@uvic.ca

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